Puupehenone congeners from an indo-pacific hyrtios sponge.

  title={Puupehenone congeners from an indo-pacific hyrtios sponge.},
  author={Ivette C Pi{\~n}a and Miranda L. Sanders and Phillip Crews},
  journal={Journal of natural products},
  volume={66 1},
An investigation of the constituents from an Indonesian Hyrtios sponge has provided new insights about the chemistry and biology of the puupehenones, a unique class of merosesquiterpenes. The parent compound, puupehenone (2), has been repeatedly encountered in sponges from four distinct orders. In this study we characterized three compounds, (+)-(5S,8S,9R,10S)-20-methoxypuupehenone (3), (+)-(5S,8S,10S)-20-methoxy-9,15-ene-puupehenol (4), and (+)-(5S,8S,9R,10S)-15,20-dimethoxypuupehenol (5… CONTINUE READING

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