Putting the Predictive Toxicology Challenge Into Perspective: Reflections on the Results

  title={Putting the Predictive Toxicology Challenge Into Perspective: Reflections on the Results},
  author={Romualdo Benigni and Alessandro Giuliani},
  volume={19 10},
MOTIVATION Chemical carcinogenicity is of primary interest, because it drives much of the current regulatory actions regarding new and existing chemicals, and its experimental determination involves time-consuming and expensive animal testing. Both academia and private companies are actively trying to develop SAR and QSAR models. This paper reviews the new Predictive Toxicology Challenge (PTC) results, by putting them into the context of previous attempts. RESULTS A marked dependency of the… CONTINUE READING
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