Putting life on hold-for how long? Profound hypothermic cardiopulmonary bypass in a Swine model of complex vascular injuries.

@article{Alam2008PuttingLO,
  title={Putting life on hold-for how long? Profound hypothermic cardiopulmonary bypass in a Swine model of complex vascular injuries.},
  author={Hasan B Alam and Michael Duggan and Yongqing Li and Konstantinos Spaniolas and Baoling Liu and Malek Tabbara and Marc A Demoya and Elizabeth A Sailhamer and Christian C. Shults and George C. Velmahos},
  journal={The Journal of trauma},
  year={2008},
  volume={64 4},
  pages={
          912-22
        }
}
BACKGROUND Rapid induction of profound hypothermia for emergency preservation and resuscitation can improve survival from uncontrolled lethal hemorrhage in large animal models. We have previously demonstrated that profound hypothermia (10 degrees C) must be induced rapidly (2 degrees C/min) and reversed gradually (0.5 degrees C/min) for best results. However, the maximum duration of hypothermic arrest in a clinically relevant trauma model remains unknown. METHODS Uncontrolled lethal… CONTINUE READING
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