Putrescine as an important source of GABA in the postnatal rat subventricular zone

@article{Sequerra2007PutrescineAA,
  title={Putrescine as an important source of GABA in the postnatal rat subventricular zone},
  author={Eduardo B Sequerra and Patrı́cia Franca Gardino and C Hedin-Pereira and Fernando Garcia de Mello},
  journal={Neuroscience},
  year={2007},
  volume={146},
  pages={489-493}
}
The subventricular zone (SVZ) is a neurogenic region that continually gives rise to olfactory bulb (OB) GABAergic interneurons in mammals. The newly generated neuroblasts already express GABA while migrating to this structure along the rostral migratory stream (RMS). Here, we investigate in early postnatal rat if SVZ/RMS cells undertake the same synthetic pathway by which GABA is produced in differentiated neurons, i.e. the decarboxylation of glutamate by the glutamic acid decarboxylase (GAD… Expand
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