Putatively Functional PLCE1 Variants and Susceptibility to Esophageal Squamous Cell Carcinoma (ESCC): A Case–Control Study in Eastern Chinese Populations

@article{Hu2011PutativelyFP,
  title={Putatively Functional PLCE1 Variants and Susceptibility to Esophageal Squamous Cell Carcinoma (ESCC): A Case–Control Study in Eastern Chinese Populations},
  author={Haichuan Hu and Jingmin Yang and Yihua Sun and Yajun Yang and Ji Qian and Li Jin and Mengyun Wang and Rui Bi and MS RuoxinZhang and Mei-ling Zhu and PhD Menghong Sun and Hongxia Ma and PhD Qingyi Wei and Guoliang Jiang and PhD Xiaoyan Zhou and Haiquan Chen},
  journal={Annals of Surgical Oncology},
  year={2011},
  volume={19},
  pages={2403-2410}
}
A novel variant rs2274223 located in the phospholipase C epsilon 1 (PLCE1) gene was found to be associated with risk of esophageal squamous cell carcinoma (ESCC) by 2 large-scale genome-wide association studies (GWASs) in Chinese populations. In this study, we aimed to assess such an association in an eastern Chinese population and to address its possibly… CONTINUE READING