Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans.

@article{Malik2000PutativeTC,
  title={Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans.},
  author={Harmit Singh Malik and William D. Burke and Thomas H. Eickbush},
  journal={Gene},
  year={2000},
  volume={251 2},
  pages={101-8}
}
Eukaryotic chromosomes end in short nucleotide repeats that are added by the enzyme telomerase. The catalytic subunit of telomerase has been shown to be most closely related in sequence to reverse transcriptases encoded by eukaryotic retrotransposable elements. This raises the question as to whether the telomerase subunit was present in the first eukaryotes or was derived during early eukaryote evolution from the replication machinery of a retrotransposable element. We present the sequence of a… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Divergence time estimatesscriptase complexed with an inhibitor

R. W. Levis, R. Ganesan, K. Houtchens, L. A. Tolar, F. M. Sheen
Science • 1999

Molecularposable element in all arthropods

H. Liu, K. Tamura, H. Takahashi
Mol . Biol . Evol . • 1999

unit homologs from fission yeast and human

H. S. Malik, J. P. Jones, T. H. Eickbush
1999
View 2 Excerpts

Reversing time , origin ofsteriod dehydrogenases

T. M. Nakamura, T. R. Cech
J . Steroid Biochem . Mol . Biol . • 1998
View 2 Excerpts

scriptase homolog in Arabidopsis thaliana

T. M. tran-Bryan, J. M. Sperger, K. B. Chapman, T. R. Cech
1998

, unit of telomerase

A. M. Villeneuve, N. Lauper, L. Codourey, H. Tobler
Science • 1997

An artificial intelligence of non - LTR retrotransposable elements

T. L. Bailey, C. P. Elkan
Mol . Biol . Evol . • 1997

Origin and evolutionary relationships of Sequence survey of the Giardia lamblia genome

S. S. Morse, M. L. Sogin, +4 authors H. T.
1994

Similar Papers

Loading similar papers…