Putative role of beta-1,3 glucans in Candida albicans biofilm resistance.

  title={Putative role of beta-1,3 glucans in Candida albicans biofilm resistance.},
  author={Jeniel E Nett and Leslie M Lincoln and Karen Marchillo and Randall J Massey and Kathleen Holoyda and Brian Hoff and Michelle VanHandel and David K. Andes},
  journal={Antimicrobial agents and chemotherapy},
  volume={51 2},
Biofilms are microbial communities, embedded in a polymeric matrix, growing attached to a surface. Nearly all device-associated infections involve growth in the biofilm life style. Biofilm communities have characteristic architecture and distinct phenotypic properties. The most clinically important phenotype involves extraordinary resistance to antimicrobial therapy, making biofilm infections very difficulty to cure without device removal. The current studies examine drug resistance in Candida… CONTINUE READING


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