Putative environmental factors in Type 1 diabetes.

  title={Putative environmental factors in Type 1 diabetes.},
  author={Hans K. Akerblom and Mikael Knip},
  journal={Diabetes/metabolism reviews},
  volume={14 1},
Various environmental triggers, e.g. certain viruses and dietary factors, are thought to initiate the autoimmune process, leading to the destruction of pancreatic beta-cells and consequent Type 1 diabetes. A genetic predisposition is another prerequisite allowing the autoimmune process to progress. Twin studies, major geographical variations in incidence rates, temporal trends in the incidence and findings in migrant studies indicate that environmental factors play a crucial role in the… CONTINUE READING


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