Purpurin Suppresses Candida albicans Biofilm Formation and Hyphal Development

  title={Purpurin Suppresses Candida albicans Biofilm Formation and Hyphal Development},
  author={Paul Wai-Kei Tsang and H. M. H. N. Bandara and W K Fong},
  booktitle={PloS one},
A striking and clinically relevant virulence trait of the human fungal pathogen Candida albicans is its ability to grow and switch reversibly among different morphological forms. Inhibition of yeast-to-hypha transition in C. albicans represents a new paradigm for antifungal intervention. We have previously demonstrated the novel antifungal activity of purpurin against Candida fungi. In this study, we extended our investigation by examining the in vitro effect of purpurin on C. albicans… CONTINUE READING


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