Purpura fulminans: recognition, diagnosis and management

@article{Chalmers2011PurpuraFR,
  title={Purpura fulminans: recognition, diagnosis and management},
  author={E. Chalmers and P. Cooper and K. Forman and C. Grimley and K. Khair and A. Minford and M. Morgan and A. Mumford},
  journal={Archives of Disease in Childhood},
  year={2011},
  volume={96},
  pages={1066 - 1071}
}
Purpura fulminans (PF) is a haematological emergency in which there is skin necrosis and disseminated intravascular coagulation. This may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. PF may complicate severe sepsis or may occur as an autoimmune response to otherwise benign childhood infections. PF may also be the presenting symptom of severe heritable deficiency of the natural anticoagulants protein C or protein S. Early… Expand
139 Citations
Purpura Fulminans: Mechanism and Management of Dysregulated Hemostasis.
  • 28
Purpura Fulminans in the Setting of Klebsiella Pneumoniae Bacteremia and Acetaminophen Overdose
  • Highly Influenced
  • PDF
Skin Necrosis and Purpura Fulminans in Children With and Without Thrombophilia—A Tertiary Center's Experience
  • 2
Purpura Fulminans in an adult with Pseudomonas aeruginosa septicemia
  • Highly Influenced
  • PDF
Streptococcus pneumoniae-induced purpura fulminans in a woman with functional asplenia.
  • 5
  • Highly Influenced
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 66 REFERENCES
Dermatopathology of skin necrosis associated with purpura fulminans.
  • 79
Current management of purpura fulminans: a multicenter study.
  • 74
The differential diagnosis of purpura from a morphologic perspective.
  • 35
Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies.
  • 186
Effect of the Factor V Leiden mutation on the severity of meningococcal disease.
  • 82
Hemostasis and thrombosis in critically ill children.
  • 24
...
1
2
3
4
5
...