Purkinje cells in awake behaving animals operate at the upstate membrane potential

@article{Schonewille2006PurkinjeCI,
  title={Purkinje cells in awake behaving animals operate at the upstate membrane potential},
  author={Martijn Schonewille and Sara Khosrovani and Beerend H. J. Winkelman and Freek E Hoebeek and Marcel T. G. de Jeu and Inger Margit Larsen and Job van der Burg and Matthew T. Schmolesky and Maarten A. Frens and Chris I. De Zeeuw},
  journal={Nature Neuroscience},
  year={2006},
  volume={9},
  pages={459-461}
}
To the Editor: Over the last decades, cellular bistability or multistable states of the membrane potential have been demonstrated both in vitro and in vivo for different types of neurons throughout the brain, and various functions have been proposed for this phenomenon1,2. Recently, Loewenstein et al.3 proposed that bistability in Purkinje cells has a key role in the short-term processing and storage of sensorimotor information in the cerebellar cortex and that complex spikes may act as a… CONTINUE READING
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