Purinoceptor-mediated calcium mobilization and proliferation in HaCaT keratinocytes.

  title={Purinoceptor-mediated calcium mobilization and proliferation in HaCaT keratinocytes.},
  author={Woon Kyu Lee and Seong Woo Choi and Hwa Ryung Lee and Edward K. Lee and Kwang Hyuck Lee and Hea O K Kim},
  journal={Journal of dermatological science},
  volume={25 2},
To investigate the effect of nucleotides on cytosolic free calcium mobilization and proliferation activity in HaCaT keratinocytes, nucleotides-induced intracellular free calcium concentration ([Ca(2+)](i)) and cell proliferation observed. [Ca(2+)](i) to the extracellular nucleotides was determined using Ca(2+) sensitive indicator, Fura-2/AM with digital video fluorescence imaging microscopy, and cell proliferation was evaluated by counting of cell number. An adenosine 5'-triphosphate (ATP… CONTINUE READING