Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: distribution and pharmacology.

@article{LePard1997PurinergicFE,
  title={Purinergic fast excitatory postsynaptic potentials in myenteric neurons of guinea pig: distribution and pharmacology.},
  author={Kathy J. LePard and E Messori and James J Galligan},
  journal={Gastroenterology},
  year={1997},
  volume={113 5},
  pages={1522-34}
}
BACKGROUND & AIMS Adenosine triphosphate (ATP) acting at P2 receptors mediates some fast excitatory postsynaptic potentials (fEPSPs) in myenteric neurons of guinea pig ileum. The present studies investigate the distribution of purinergic fEPSPs along the length of the gut and characterize the P2-receptor subtype mediating fEPSPs. METHODS Conventional intracellular electrophysiological methods were used to record from myenteric neurons in vitro. RESULTS At a membrane potential of -97 +/- 1… CONTINUE READING