Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types

@article{Rathbone1992PurineNA,
  title={Purine nucleosides and nucleotides stimulate proliferation of a wide range of cell types},
  author={Michel Piers Rathbone and Pamela J. Middlemiss and John W. Gysbers and S Deforge and Penny C Costello and Rolando F. Del Maestro},
  journal={In Vitro Cellular & Developmental Biology - Animal},
  year={1992},
  volume={28},
  pages={529-536}
}
Presumptive astrocytes isolated from 10-day white Leghorn chick embryos, Factor VIII-positive human brain capillary endothelial cells, meningeal fibroblasts from 10-day chick embryos, Swiss mouse 3T3 cells, and human astrocytoma cell lines, SKMG-1 and U373, were rendered quiescent when placed in culture medium that contained 0 or 0.2% serum for 48 h; their proliferation was markedly reduced and they incorporated [3H]thymidine at a low rate. [3H]Thymidine incorporation and cell proliferation… CONTINUE READING

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