Purine nucleoside formation in rat skeletal muscle fiber types.

@article{Arabadjis1993PurineNF,
  title={Purine nucleoside formation in rat skeletal muscle fiber types.},
  author={P. G. Arabadjis and P. Tullson and R. Terjung},
  journal={The American journal of physiology},
  year={1993},
  volume={264 5 Pt 1},
  pages={
          C1246-51
        }
}
To determine the capacity for purine nucleotide degradation among skeletal muscle fiber types, we established energy-depleted conditions in muscles of the rat hindlimb by inducing muscle contraction during ischemia. After 5, 10, 15, or 20 min of ischemic contractions, representative muscle sections were freeze-clamped and analyzed for purine nucleotides, nucleosides, and bases. Fast-twitch muscle sections accumulated about fourfold more IMP than the slow-twitch red soleus muscle. Inosine begins… Expand
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