Purine metabolism in high and low uric acid lines of chickens: phosphoribosylpyrophosphate (PRPP) synthetase activities and PRPP pool sizes.

@article{McFarland1983PurineMI,
  title={Purine metabolism in high and low uric acid lines of chickens: phosphoribosylpyrophosphate (PRPP) synthetase activities and PRPP pool sizes.},
  author={Douglas C. McFarland and Craig N. Coon},
  journal={Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine},
  year={1983},
  volume={174 3},
  pages={407-14}
}
Phosphoribosylpyrophosphate synthetase activities were examined in liver and kidney tissues of two genetic lines of chickens selected for their plasma uric acid levels. Previous work demonstrated that the high uric acid line (HUA) has significantly greater de novo uric acid synthesis rates in kidney tissue compared to the low uric acid line (LUA). In… CONTINUE READING