Purine metabolism in Toxoplasma gondii.

  title={Purine metabolism in Toxoplasma gondii.},
  author={Eric L. Krug and J{\"u}rgen Marr and Randolph L. Berens},
  journal={The Journal of biological chemistry},
  volume={264 18},
We have studied the incorporation and interconversion of purines into nucleotides by freshly isolated Toxoplasma gondii. They did not synthesize nucleotides from formate, glycine, or serine. The purine bases hypoxanthine, xanthine, guanine, and adenine were incorporated at 9.2, 6.2, 5.1, and 4.3 pmol/10(7) cells/h, respectively. The purine nucleosides adenosine, inosine, guanosine, and xanthosine were incorporated at 110, 9.0, 2.7, and 0.3 pmol/10(7) cells/h, respectively. Guanine, xanthine… CONTINUE READING


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