Purine and glycine metabolism by purinolytic clostridia.

@article{Drre1983PurineAG,
  title={Purine and glycine metabolism by purinolytic clostridia.},
  author={Peter D{\"u}rre and Jan Remmer Andreesen},
  journal={Journal of bacteriology},
  year={1983},
  volume={154 1},
  pages={192-9}
}
Cell extracts of Clostridium acidiurici, C. cylindrosporum, and C. purinolyticum converted purine, hypoxanthine, 2-hydroxypurine, 6,8-dihydroxypurine, and uric acid into xanthine by the shortest possible route. Adenine was transformed to xanthine only by C. purinolyticum, whereas the other two species formed 6-amino-8-hydroxypurine, which was neither deaminated nor hydroxylated further. 8-Hydroxypurine was formed from purine by all three species. Xanthine dehydrogenase activity was… CONTINUE READING
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