Purine Nucleotide Metabolism in Cultured Rat Skeletal and Heart Muscle: a Comperative Study of the Mechanisms of Atp Conservation: 238

Primary rat skeletal and cardiomyocyte cultures exhibited de novo and salvage synthesis of purine nucleotides. In the myotube cultures, the rate of de novo synthesis was faster but the rate of salvage synthesis from adenosine was slower. The rate of salvage nucleotide synthesis from adenine and hypoxanthine was similar in the two tissues, but was markedly… (More)