Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles.

  title={Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles.},
  author={Barrett J. Nehilla and Magnus Bergkvist and Ketul C. Popat and Tejal A. Desai},
  journal={International journal of pharmaceutics},
  volume={348 1-2},
The intent of this work was to synthesize and comprehensively characterize ubiquinone-loaded, surfactant-free biodegradable poly(lactic-co-glycolic acid) (PLGA) nanoparticles in vitro. Surfactant-free, empty and ubiquinone (CoQ10)-loaded biodegradable nanoparticles were synthesized by nanoprecipitation, and the physicochemical properties of these nanoparticles were analyzed with a variety of techniques. Nanoprecipitation consistently yielded individual, sub-200nm, surfactant-free empty and… CONTINUE READING


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