Purified Secretory Vesicles from Bovine Neurohypophyses

  • Torben Srermark
  • Published 2003


Purified secretory vesicles isolated from bovine neurohypophyses take up Na+ under the same circumstances where an efflux of Ca 2 + takes place, suggesting a Na+/Ca 2 + exchange. Potassium cannot substitute for Na+ in this process. Also, a Ca 2 +/Ca 2 + exchange can occur. Inhibiting the latter process by Mg 2 + allowed to estimate an apparent KM of 0.7 uM… (More)


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