Purified Liver Microsomal NADPH-Cytochrome P-450 Reductase

  title={Purified Liver Microsomal NADPH-Cytochrome P-450 Reductase},
  • Published 2002
NADPH-cytochrome P-450 reductase was isolated from liver microsomes of phenobarbital-induced rats. The enzyme exhibits an apparent minimal molecular weight of 76,000 as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and contains 1 molecule each of FMN and FAD. Trypsin treatment of the reductase yields an enzyme with an apparent… CONTINUE READING