Purification of two plaque variants of Sindbis virus

  title={Purification of two plaque variants of Sindbis virus},
  author={Henry R. Bose and G. Z. Carl and Bernard P. Sagik},
  journal={Archiv f{\"u}r die gesamte Virusforschung},
A method for concentrating and purifying enveloped viruses is described. Its salient feature is the use of an antihost immunoadsorbent column. Purified virus preparations were obtained in which viral-specific proteins per/mg total protein were enriched 800-fold, while host-specific complement fixing material became undetectable.