Purification of recombinant adenovirus type 3 dodecahedric virus-like particles for biomedical applications using short monolithic columns.

@article{Urbas2011PurificationOR,
  title={Purification of recombinant adenovirus type 3 dodecahedric virus-like particles for biomedical applications using short monolithic columns.},
  author={Lidija Urbas and Barbara Lah Jarc and Milo{\vs} Barut and Monika Zochowska and Jadwiga Chroboczek and Boris Pihlar and Ewa Szolajska},
  journal={Journal of chromatography. A},
  year={2011},
  volume={1218 17},
  pages={2451-9}
}
Adenovirus type 3 dodecahedric virus-like particles (Ad3 VLP) are an interesting delivery vector. They penetrate animal cells in culture very efficiently and up to 300,000 Ad3 VLP can be observed in one cell. The purification of such particles usually consists of several steps. In these work we describe the method development and optimization for the… CONTINUE READING