Purification of natural antikeratin autoantibodies from normal human serum and their effect on human keratinocytes cultured in vitro.

Abstract

BACKGROUND Antikeratin (AK) autoantibodies, circulating antibodies against epidermal keratins, have been detected in all normal human sera. However, direct evidence on the biological significance of AK autoantibodies is still lacking. OBJECTIVES To purify AK autoantibodies from human serum and to make a preliminary study of their biological effects on… (More)

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@article{Li2001PurificationON, title={Purification of natural antikeratin autoantibodies from normal human serum and their effect on human keratinocytes cultured in vitro.}, author={C. X. Li and Y. H. Wan and Sheng-Chai Chi and G. Wang and L C Sun and Y. G. Zhang and X. D. Zhao and Tao Gao and Y. F. Liu}, journal={The British journal of dermatology}, year={2001}, volume={145 5}, pages={737-48} }