Purification of bufadienolides from the skin of Bufo bufo gargarizans Cantor with positively charged C18 column.


As a kind of promising anticancer compounds, the preparation of bufadienolides is a hot study spot. However, due to the complexity of biological sample, the purification of bufadienolides from a crude sample (toad skin) is a tough work. In this paper, we reported a new way based on positively charged C18 material (XCharge C18) to quickly separate and purify… (More)
DOI: 10.1016/j.jpba.2014.01.002