Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membrane.

@article{Berndt1985PurificationAP,
  title={Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membrane.},
  author={Michael C. Berndt and Christopher Gregory and A Kabral and Heddy Zola and Donna J Fournier and Peter A. Castaldi},
  journal={European journal of biochemistry},
  year={1985},
  volume={151 3},
  pages={637-49}
}
Human platelet glycoprotein Ib (GP Ib) is a major integral membrane protein that has been identified as the platelet-binding site mediating the factor VIII/von Willebrand-factor-dependent adhesion of platelets to vascular subendothelium. Recent evidence suggests that GP Ib is normally complexed with another platelet membrane protein, GP IX. In this study… CONTINUE READING