Purification and molecular cloning of a platelet aggregation inhibitor from the snake (Agkistrodon halys brevicaudus) venom.

Abstract

A platelet glycoprotein IIb-IIIa (GP IIb-IIIa) antagonist, salmosin, was purified to homogeneity from Korean snake (Agkistrodon halys brevicaudus) venom by means of chromatographic fractionations. We have isolated the cDNA encoding salmosin by using the cDNA library of the snake venom gland and analyzed its complete nucleotide sequence. The molecular… (More)

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@article{Kang1998PurificationAM, title={Purification and molecular cloning of a platelet aggregation inhibitor from the snake (Agkistrodon halys brevicaudus) venom.}, author={In-chol Kang and K. H. Chung and S. J. Lee and Y. Yun and Hyung-in Moon and D. S. Kim}, journal={Thrombosis research}, year={1998}, volume={91 2}, pages={65-73} }