Purification and immunophenotypic characterization of murine B10 B cells.

Abstract

Regulatory B10 cells represent a rare CD1d(hi)CD5(+) IL-10-secreting B cell subset in mice which is induced to produce IL-10 after 5 h of in vitro stimulation with a combination of B cell mitogen and chemical stimulants. Although B10 cells only constitute 1-2 % of splenic CD19(+) B cells, they play important roles in controlling T cell-mediated immune… (More)
DOI: 10.1007/978-1-4939-1161-5_3

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