Purification and characterization of asparaginase II from Saccharomyces cerevisiae cloned in Pichia pastoris: a study on a possible antileukemic drug

Abstract

Introduction Bacterial asparaginase obtained from Escherichia coli and Erwinia chrysanthemi are used as medicine to treat acute lymphocytic leukemia and non-Hodgkin lymphoma. Despite the therapeutic properties of such enzymes there have been reports on adverse reactions, eventually so severe as to impede some patients of using the medicine. Besides, the… (More)

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Cite this paper

@inproceedings{Giro2014PurificationAC, title={Purification and characterization of asparaginase II from Saccharomyces cerevisiae cloned in Pichia pastoris: a study on a possible antileukemic drug}, author={Luciana Facchinetti de Castro Gir{\~a}o and Surza Lucia Gonçalves da Rocha and Ricardo Teixeira and Maria Antonieta Ferrara and Jonas Perales and Elba Pinto da Silva Bon}, year={2014} }