Purification and characterization of a protein tyrosine phosphatase which dephosphorylates the nicotinic acetylcholine receptor.

@article{Mei1991PurificationAC,
  title={Purification and characterization of a protein tyrosine phosphatase which dephosphorylates the nicotinic acetylcholine receptor.},
  author={Lin Mei and Richard L. Huganir},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 24},
  pages={16063-72}
}
The nicotinic acetylcholine receptor (nAChR) is phosphorylated to a high stoichiometry on tyrosine residues both in vitro and in vivo. Moreover, tyrosine phosphorylation has been shown to regulate the functional properties of the receptor. We report here the purification and characterization of a protein tyrosine phosphatase that dephosphorylates tyrosine… CONTINUE READING