Purification and characterization of a novel restricted antigen expressed by normal and transformed human colonic epithelium.

@article{Catimel1996PurificationAC,
  title={Purification and characterization of a novel restricted antigen expressed by normal and transformed human colonic epithelium.},
  author={Bruno Catimel and Gerd Ritter and Sydney Welt and L. John Old and Leonard S. Cohen and Maureen Nerrie and Stanley J. White and John K. Heath and Barbara Demediuk and Teresa Domagala and Faye T Lee and Andrew Mark Scott and Guanghuan Tu and Hong Tai Ji and Robert L. Moritz and Richard J. Simpson and Antony W. Burgess and Edouard C Nice},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 41},
  pages={25664-70}
}
A cell surface antigen that is expressed by normal and 95% of transformed colonic epithelium and is recognized by the monoclonal antibody A33 (Welt, S., Divgi, C. R., Real, F. X., Yeh, S. D., Garin-Chesa, P., Finstad, C. L., Sakamoto, J., Cohen, A., Sigurdson, E. R., Kemeny, N., Carswell, E. A., Oettgen, H. F., and Old, L. J. (1990) J. Clin. Oncol. 8, 1894-1906) has been purified to homogeneity from the human colonic carcinoma cell line LIM1215. The A33 protein was purified from Triton X-114… CONTINUE READING

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