Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits.

@article{Parra1990PurificationAC,
  title={Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits.},
  author={Francisco Vargas Parra and Miguel Prieto},
  journal={Journal of virology},
  year={1990},
  volume={64 8},
  pages={4013-5}
}
The causative viral agent of a lethal rabbit hemorrhagic disease has been purified and characterized. In negative-stained preparations, the virions were icosahedral, measured 27 to 35 nm in diameter, were without an envelope, and showed 10 peripheral cup-shaped depressions. The major structural protein was 60 kilodaltons, which constitutes a unique characteristic of the Caliciviridae.