Purification and Characterization of a Proteasome from the Hyperthermophilic Archaeon Pyrococcus furiosus.

@article{Bauer1997PurificationAC,
  title={Purification and Characterization of a Proteasome from the Hyperthermophilic Archaeon Pyrococcus furiosus.},
  author={Michael W. Bauer and Siefgfried Bauer and Robert B. Kelly},
  journal={Applied and environmental microbiology},
  year={1997},
  volume={63 3},
  pages={1160-4}
}
A 640-kDa proteasome consisting of (alpha) (25-kDa) and (beta) (22-kDa) subunits, and with a temperature optimum of 95(deg)C, was purified from crude cell extracts of a hyperthermophilic archaeon, Pyrococcus furiosus. Although this is the fourth member of the kingdom Euryarchaeota (and the first hyperthermophile) found to contain a proteasome, none has been identified among the members of the kingdom Crenarchaeota. 

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