Purification and Characterization of Antioxidant Peptides from Oyster (Saccostrea cucullata) Hydrolysate and the Anticancer Activity of Hydrolysate on Human Colon Cancer Cell Lines

@article{Umayaparvathi2013PurificationAC,
  title={Purification and Characterization of Antioxidant Peptides from Oyster (Saccostrea cucullata) Hydrolysate and the Anticancer Activity of Hydrolysate on Human Colon Cancer Cell Lines},
  author={Shanmugam Umayaparvathi and Mahashanon Arumugam and Sankaran Meenakshi and Gerald Draeger and Andreas Kirschning and Thangavel Balasubramanian},
  journal={International Journal of Peptide Research and Therapeutics},
  year={2013},
  volume={20},
  pages={231-243}
}
The focus of the study was to investigate antioxidant activity and characterize antioxidant peptides from oyster (Saccostrea cucullata) protein hydrolysate. The protease hydrolysate of oyster exhibited strong potential to donate hydrogen and was able to scavenge Hydrogen peroxide, Hydroxyl and DPPH radicals. Due to the high antioxidant potential, hydrolysate was purified in Sephadex G-25 gel filtration chromatography. The active peptide fraction was further purified by UPLC-MS. Totally seven… CONTINUE READING