Purification, monoclonal antibody production and structural analyses of human progesterone receptors.

Abstract

Progesterone receptors (PR) from human breast cancer cells have been purified, and used as antigens to generate anti-PR monoclonal antibodies. Immunologic and in situ photoaffinity labeling methods were then used to study receptor structure, and we conclude that native human PR consist of two independent 8S receptors: one 8S subtype contains B-proteins (120… (More)

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@article{Horwitz1988PurificationMA, title={Purification, monoclonal antibody production and structural analyses of human progesterone receptors.}, author={Kathryn B. Horwitz}, journal={Journal of steroid biochemistry}, year={1988}, volume={31 4B}, pages={573-8} }