Purification, crystallization and preliminary X-ray crystallographic analysis of the CIDE-N domain of Fsp27.

Abstract

Fsp27, a member of the CIDE protein family which is selectively expressed in adipocytes, has emerged as a novel regulator for unilocular lipid droplet (LD) formation, lipid metabolism, differentiation of adipocytes and insulin sensitivity. An LD is a subcellular compartment that is used by adipocytes for the efficient storage of fats. The CIDE-N domain of… (More)
DOI: 10.1107/S1744309112043989

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