Purification, crystallization and preliminary X-ray crystallographic analysis of the transport unit of the monomeric autotransporter AIDA-I from Escherichia coli.

@article{Gawarzewski2013PurificationCA,
  title={Purification, crystallization and preliminary X-ray crystallographic analysis of the transport unit of the monomeric autotransporter AIDA-I from Escherichia coli.},
  author={I. Gawarzewski and Britta Tschapek and A. Hoeppner and J. Jose and S. Smits and L. Schmitt},
  journal={Acta crystallographica. Section F, Structural biology and crystallization communications},
  year={2013},
  volume={69 Pt 10},
  pages={
          1159-62
        }
}
  • I. Gawarzewski, Britta Tschapek, +3 authors L. Schmitt
  • Published 2013
  • Biology, Medicine
  • Acta crystallographica. Section F, Structural biology and crystallization communications
  • The adhesin involved in diffuse adherence (AIDA-I) from Escherichia coli belongs to the group of autotransporters, specifically the type Va secretion system (T5aSS). All autotransporter systems contain a C-terminal β-domain, which forms a barrel-like structure in the outer membrane with a hydrophilic pore allowing passenger translocation across the outer membrane. The passenger domain harbours the biological activity in the extracellular space and functions, for example, as an adhesin, an… CONTINUE READING
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