Pure red cell aplasia induced by epoetin zeta

  title={Pure red cell aplasia induced by epoetin zeta},
  author={Vincenzo Panichi and Guido Ricchiuti and Alessia Scatena and Lucia Del Vecchio and Francesco Locatelli},
  booktitle={Clinical kidney journal},
Pure red cell aplasia (PRCA) may develop in patients with chronic kidney disease receiving erythropoiesis-stimulating agents (ESA). We report on a 72-year-old patient who developed hypo-proliferative anaemia unresponsive to ESA following the administration of epoetin zeta subcutaneously for 7 months. On the basis of severe isolated hypoplasia of the erythroid line in the bone marrow and high-titre neutralizing anti-erythropoietin antibodies (Ab), a diagnosis of Ab-mediated PRCA was made… CONTINUE READING


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Antibodymediated pure red cell aplasia in chronic kidney disease patients receiving erythropoiesis-stimulating agents: new insights

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  • Kidney Int
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