Pupil size following dark adaptation in patients with retinitis pigmentosa.

  title={Pupil size following dark adaptation in patients with retinitis pigmentosa.},
  author={Adriana Berezovsky and Solange R Salom{\~a}o and David G. Birch},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  volume={34 8},
According to the equivalent light hypothesis, molecular defects in the photoreceptor lead to a continuous activation of the photoreceptor cascade in a manner equivalent to real light. The consequences in diseases such as retinitis pigmentosa (RP) are as disruptive to the cells as real light. Two forms of the equivalent light hypothesis can be distinguished: strong - mutations in rhodopsin or other cascade proteins in some forms of RP continuously excite the visual phototransduction cascade… CONTINUE READING


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