Pupil dilatation assay by tropicamide is modulated by apolipoprotein E epsilon 4 allele dosage in Alzheimer's disease.

@article{Arai1996PupilDA,
  title={Pupil dilatation assay by tropicamide is modulated by apolipoprotein E epsilon 4 allele dosage in Alzheimer's disease.},
  author={H Arai and Masaomi Terajima and Toshiyuki Nakagawa and Susumu Higuchi and Hirotsugu Mochizuki and Hidenao Sasaki},
  journal={Neuroreport},
  year={1996},
  volume={7 4},
  pages={
          918-20
        }
}
The mydriatic response to dilute tropicamide was studied in 25 Japanese patients with Alzheimer's disease (AD), 13 patients with non-AD neurological diseases (non-AD) and 11 normal elderly subjects (control). Although the changes in resting pupil diameter and area over baseline were significantly greater (p < 0.05) in AD patients than in non-AD patients and controls, there was considerable overlap between the three groups. The change in resting pupil area was significantly greater (p < 0.05) in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-9 OF 9 CITATIONS

Oculo-visual changes and clinical considerations affecting older patients with dementia.

  • Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians
  • 2015

Ocular biomarkers for early detection of Alzheimer's disease.

  • Journal of Alzheimer's disease : JAD
  • 2010
VIEW 2 EXCERPTS
CITES BACKGROUND