Punish the parent not the progeny.

@article{Elrick2005PunishTP,
  title={Punish the parent not the progeny.},
  author={L. Elrick and H. J{\o}rgensen and J. Mountford and T. Holyoake},
  journal={Blood},
  year={2005},
  volume={105 5},
  pages={
          1862-6
        }
}
Chronic myeloid leukemia (CML) is sustained by a rare population of primitive, quiescent, BCR-ABL+ cells and represents an excellent example of a malignancy in which tumor-initiating cells represent the key to disease eradication. CML is also the first malignancy for which targeted therapy has replaced conventional chemotherapy. Within a vast excess of proliferating progenitor cells that express breakpoint cluster region-abelson (BCR-ABL) and are exquisitely sensitive to the tyrosine kinase… Expand
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