Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice.

@article{Choi2011PunicaGP,
  title={Punica granatum protects against oxidative stress in PC12 cells and oxidative stress-induced Alzheimer's symptoms in mice.},
  author={Soo Jung Choi and Ju-Hyun Lee and Ho Jin Heo and Hong Yon Cho and Hye Kyung Kim and C -K Kim and Myeong Ok Kim and Soo Hwan Suh and D B Shin},
  journal={Journal of medicinal food},
  year={2011},
  volume={14 7-8},
  pages={
          695-701
        }
}
Alzheimer's disease (AD) is a progressive degenerative brain disorder that is characterized by neuronal loss, neurofibrillary tangles, and the abnormal deposition of senile plaque and amyloid β peptide (Aβ). The brains of AD patients are under intense oxidative stress. The overproduction of Aβ leads to Aβ-associated free radical oxidative stress. In this study, the antioxidative and neuronal protective effects of Punica granatum extract were investigated against oxidative stress-induced… CONTINUE READING
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