Pump and leak in regulation of fluid transport in rabbit cornea.

@article{Riley1985PumpAL,
  title={Pump and leak in regulation of fluid transport in rabbit cornea.},
  author={Michael V. Riley},
  journal={Current eye research},
  year={1985},
  volume={4 4},
  pages={
          371-6
        }
}
  • M. Riley
  • Published 1 April 1985
  • Biology, Medicine
  • Current eye research
Rabbit corneas were isolated, denuded of epithelium, and perfused on the anterior and posterior surfaces with Krebs Ringer-bicarbonate with additions of 50 microM H2O2, 125 microM BCNU, or 100 microM ouabain. The permeability of the corneal endothelium to labelled mannitol and inulin was determined by adding these compounds to the endothelial perfusate and measuring the rate of appearance of radioactivity in the anterior perfusate. Both H2O2 and BCNU increased the flux of mannitol and inulin… 
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