Pump Up the Volume: Could Excessive Neural Gain Explain Tinnitus and Hyperacusis?

  title={Pump Up the Volume: Could Excessive Neural Gain Explain Tinnitus and Hyperacusis?},
  author={Hannah Brotherton and Christopher J. Plack and Michael R. D. Maslin and Roland Schaette and Kevin James Munro},
  journal={Audiology and Neurotology},
  pages={273 - 282}
Naturally occurring stimuli can vary over several orders of magnitude and may exceed the dynamic range of sensory neurons. As a result, sensory systems adapt their sensitivity by changing their responsiveness or ‘gain'. While many peripheral adaptation processes are rapid, slow adaptation processes have been observed in response to sensory deprivation or elevated stimulation. This adaptation process alters neural gain in order to adjust the basic operating point of sensory processing. In the… 

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