Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos.

@article{Barker1992PumilioIE,
  title={Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos.},
  author={Dick Barker and Caihong Wang and J Moore and Lucy Dickinson and Ruth Lehmann},
  journal={Genes & development},
  year={1992},
  volume={6 12A},
  pages={2312-26}
}
The Drosophila gene pumilio is expressed maternally, and its function is essential during early embryogenesis for the formation of abdominal segments. Our molecular analysis reveals that pumilio is a large gene that encodes a protein of 160 kD whose RNA is enriched at the posterior pole of the egg. As with pumilio, the maternal effect gene nanos is specifically required for abdomen formation. The Nanos protein is expressed in a posterior-to-anterior concentration gradient in the developing… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 95 extracted citations

Similar Papers

Loading similar papers…