Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes.

Abstract

Type 2 diabetes (T2DM) results when increases in beta cell function and/or mass cannot compensate for rising insulin resistance. Numerous studies have documented the longitudinal changes in metabolism that occur during the development of glucose intolerance and lead to T2DM. However, the role of changes in insulin secretion, both amount and temporal pattern… (More)
DOI: 10.1016/j.mam.2015.01.003

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Cite this paper

@article{Satin2015PulsatileIS, title={Pulsatile insulin secretion, impaired glucose tolerance and type 2 diabetes.}, author={Leslie S. Satin and Peter C Butler and Joon Ha and Arthur S Sherman}, journal={Molecular aspects of medicine}, year={2015}, volume={42}, pages={61-77} }