Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting.

@article{Prksen1995PulsatileIS,
  title={Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting.},
  author={Niels K P\orksen and S. Rahman. L. C. Munn and Jeffery L. Steers and Stephen J. Vore and Johannes D. Veldhuis and Peter C Butler},
  journal={The American journal of physiology},
  year={1995},
  volume={269 3 Pt 1},
  pages={E478-88}
}
The purpose of the present study was to determine the contributions of discrete insulin secretory bursts vs. basal insulin release to total insulin secretion in vivo. Quantification of the partitioning of pulsatile and basal insulin secretion is complicated by physiological delivery of these pulses into the portal vein and the absence of validated methods of measuring the rates of pulsatile and basal insulin secretion in vivo. We therefore 1) developed a canine model with chronically implanted… CONTINUE READING

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