Pulsatile administration of gonadotropin-releasing hormone for induction of ovulation.

@article{Loucopoulos1984PulsatileAO,
  title={Pulsatile administration of gonadotropin-releasing hormone for induction of ovulation.},
  author={A Loucopoulos and Michel J Ferin and R L vande Wiele and Inge Dyrenfurth and D M Linkie and Mary Yeh and R Jewelewicz},
  journal={American journal of obstetrics and gynecology},
  year={1984},
  volume={148 7},
  pages={895-900}
}
Chronic pulsatile administration of gonadotropin-releasing hormone (GnRH) was used to induce ovulation in 12 women with various ovulatory disorders. In the first group of eight patients with normal to low baseline levels of gonadotropin, seven responded favorably to the treatment. Follicular maturation was observed in 57% of the treated cycles, and normal ovulatory cycles were induced in 24% of the patients. Two patients became pregnant. The intravenous route of administration was more… CONTINUE READING