Pulmonary veno-occlusive disease: clinical, functional, radiologic, and hemodynamic characteristics and outcome of 24 cases confirmed by histology.

@article{Montani2008PulmonaryVD,
  title={Pulmonary veno-occlusive disease: clinical, functional, radiologic, and hemodynamic characteristics and outcome of 24 cases confirmed by histology.},
  author={David Montani and Lara Achouh and Peter Dorfm{\"u}ller and J{\'e}r{\^o}me Le Pavec and Benjamin Sztrymf and Colas Tch{\'e}rakian and Anne Rabiller and Rehan Haque and Olivier Sitbon and Xavier Ja{\"i}s and Philippe Dartevelle and Sophie Ma{\^i}tre and Fr{\'e}d{\'e}rique Capron and Dominique Musset and G{\'e}rald Simonneau and Marc Humbert},
  journal={Medicine},
  year={2008},
  volume={87 4},
  pages={220-33}
}
Pulmonary veno-occlusive disease (PVOD) is defined by specific pathologic changes of the pulmonary veins. A definite diagnosis of PVOD thus requires a lung biopsy or pathologic examination of pulmonary explants or postmortem lung samples. However, lung biopsy is hazardous in patients with severe pulmonary hypertension, and there is a need for noninvasive diagnostic tools in this patient population. Patients with PVOD may be refractory to pulmonary arterial hypertension (PAH)-specific therapy… CONTINUE READING

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